刚下了avastin官网的用药指南:
# ?9 B5 U! n% T; Z6 j0 O8 W7 J3 a* l5 ?) X0 {4 f
Patients should continue treatment until disease progression or unacceptable toxicity. 0 Y' B1 ]) F: B* N, J0 F& `
1 Metastatic Colorectal Cancer (mCRC) ' P! ]2 R$ g; H+ x# x9 w, ]5 E
The recommended doses are 5 mg/kg or 10 mg/kg every 2 weeks when used in combination with
- s! R' F2 U$ \& }8 Fintravenous 5-FU-based chemotherapy. + Q6 ^; {; K( ?* v' a) |) h
• Administer 5 mg/kg when used in combination with bolus-IFL. 6 K, @. N3 }& I; Y+ V3 p9 T
• Administer 10 mg/kg when used in combination with FOLFOX4.
" ]8 H% R" _: }* C2 Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
T+ Y* `& A k$ s The recommended dose is 15 mg/kg every 3 weeks in combination with carboplatin and 6 D. S0 g8 s' f! T7 R" B9 x. s; a
paclitaxel. " g' D1 |4 c6 x5 E6 r4 v
3 Metastatic Breast Cancer (MBC) 1 B0 b1 A( E5 A j
The recommended dose is 10 mg/kg every 2 weeks in combination with paclitaxel.
: n) Z6 h6 ?2 b. I8 E4 Glioblastoma, @; E+ e* a+ ^: k% }, w6 `
The recommended dose is 10 mg/kg every 2 weeks.
# Z" ^" G5 e s; V- L9 R5 Metastatic Renal Cell Carcinoma (mRCC)
- l6 O. ^4 U% ?) J The recommended dose is 10 mg/kg every 2 weeks in combination with interferon alfa.
$ c2 }& d' X' K
1 l0 t3 J$ @* @' ^按照这个说明非小细胞腺癌的服用剂量是15mg/kg,与卡铂紫杉醇合用,avastin每三周用一次。
" A3 ~2 @& U0 U0 b$ K我妈妈是肺腺癌转肝,体重53kg,现在医生联合卡铂紫杉醇化疗了一个疗程21天。 但avastin不是一次注射的,每7天注射一次200mg,一个疗程21天注射了3次(分别是第一、八、十五天) |